Abacavir is an antiretroviral used to treat HIV/AIDS. It is available under the trade name Ziagen and in the combination formulations Trizivir (abacavir, zidovudine and lamivudine) and Kivexa/Epzicom (abacavir and lamivudine).
The presence of the HLA-B*5701 allele has been correlated with immunological hypersensitivity to Abacavir in white and black HIV-positive patients from United States.
HLA-B*5701 allele carriers in HIV-positive Hispanic patients showed a clinically-diagnosed hypersensitivity reaction to Abacavir.
Related to:
Abacavir, Dolutegravir, Lamivudine, Ziagen